- An interstice or small space, as between the cracks of the surface in certain crustaceous lichens; or as between the fibers composing organs or vessels that interlace; or as between the nervures of an insect's wing.
- [Anat. & Med] The colored ring around the nipple, or around a vesicle or pustule.
Etymology: L. areola, dim. of area: cf. F. aréole. See Area